Fumaric acid ≥99% CAS Number 110-17-8. This study investigates the relationships between the supramolecular structure and the solubility and melting point of six multicomponent crystals involving fumaric acid (FUM series) and adipic acid (ADI series). Fumaric acid for synthesis. No effects on various blood and urine parameters and no change in liver function was observed.Fumaric acid is not expected to accumulate since it plays a role in normal body It can be used as acidulant, acidity regulator, acidifier, thermal-oxidative resist auxiliary, curing accelerant and spice. Fumaric acid may be used in the preparation of L-Lysine-fumaric acid crystals. CopyCopied, InChI=1S/C4H4O4/c5-3(6)1-2-4(7)8/h1-2H,(H,5,6)(H,7,8)/b2-1+ Melting point/range: 287 °C; 3.6. Melting point-286-289. - Find MSDS or SDS, a COA, data sheets and more information. Fumaric acid is a common food additive included in many processed foods to keep them stable and to add tartness. DL-malic acid … - Find MSDS or SDS, a COA, data sheets and more information. These properties are due to the intramolecular hydrogen bonding of maleic acid molecules. Decomposes at around 230 C. Incompatible with strong oxidizing agents, bases, reducing agents. It has a fruit-like taste and has been used as a food additive. Fumaric acid for synthesis. Maleic acid, the cis isomer (I), has a melting point of 130°C and a boiling point of 160°C; fumaric acid, the trans isomer (II), has a melting point of 286°C and a boiling point of 290°C. Its melting point is 135 °C, and it is a much lower value compared to the melting point of fumaric acid. Fumaric acid occurs naturally in fumitory, bolete mushrooms, lichen and Iceland moss. Solubility (25℃) g/100gwater ≥1.0. Ash content % ≤0.03. It is an intermediate metabolite in the citric acid cycle. Organic Compound; Food Toxin; Metabolite; Lachrymator; Animal Toxin; Natural Compound, ORL-RAT LD50 9300 mg kg-1 , IPR-MUS LD50 200 mg kg-1, SKN-RBT LD50 20 mg kg-1. Chroma (in 5% ethanol) Hazen ≤15. Melting point of fumaric acid is much higher than that of maleic acid. CAS 110-17-8, EC Number 203-743-0, chemical formula HOOCCHCHCOOH. A white solid, fumaric acid occurs widely in nature. Stable at room temperature. They react in this way with all bases, both organic (for example, the amines) and inorganic. Other Information. 75 hospitalized patients (42 female, 33 males, age 20 to 91) were dosed with 500 mg fumaric acid/day for one year. oC. ... Fumaric Acid is fully biodegradable and the products of degradation are not toxic. In addition to the Thermodynamics Research Center (TRC) data available from this site, much more physical and chemical property data is available from the following TRC products: EC Number 203-743-0. Their reactions with bases, called "neutralizations", are accompanied by … PubChem Substance ID 57648052 It is used in the manufacture of medicines, drinks, food, animal feed, cleansing agents, unsaturated polyester, alkyd resins, and printing inks. Weight Average: 116.0722 Monoisotopic: 116.010958616 Chemical Formula C 4 H 4 O 4 Synonyms (2E)-2-butenedioic acid (E)-2-butenedioic acid; Fumaricum acidum D. Why do both react with bicarb? Fumaric acid has been used as a standard for the quantitative determination of phenolic compounds in nettle samples by HPLC. 286~302 . Fumaric acid is odorless with a specific and intense sour, about 1.5 times that of citric acid. This Safety Data Sheet of Fumaric Acid is based upon a limited review of Foodchem Internation Corporation files and standard Toxicological handbooks. Heavy metal (base on Pb) PPM ≤10. Fumaric acid is used as a flavoring, because it is the sourest tasting of the organic acids.Three parts of fumaric acid are as sour as five parts of citric acid. Articles of fumaric acid are included as well. In fumaric acid the carboxylic acid groups are trans (E) and in maleic acid they are cis (Z). Fumarate can also refer to the C 4H 2O 4 ion (in solution). From Wikipedia. Linear Formula HOOCCH=CHCOOH . fumaric acid ,Butenedioic acid , Allomaleic acid , Boletic acid , Donitic acid , Lichenic acid. Melting Point . Visit ChemicalBook To find more Fumaric acid(110-17-8) information like chemical properties,Structure,melting point,boiling point,density,molecular formula,molecular weight, physical properties,toxicity information,customs codes. Registration dossier . Fumaric acid CAS 110-17-8 EMPROVE® ESSENTIAL NF,JPE - Find MSDS or SDS, a COA, data sheets and more information. Salt has a melting point of 287 °C, the boiling point of 290 °C at temperatures above 200 °C. C(=C/C(=O)O)\C(=O)O tested according to USP/NF, Fumaric acid Usage: The solubility of fumaric acid-CWS is 65% higher than that of original fumaric acid. Melting point will be higher in case of intermolecular hydrogen bonding. Its acidity is 2.5 times of that of citric acid… [email protected] 39021709 . Fusion (melting) point: Δ c H° solid: Enthalpy of combustion of solid at standard conditions: Δ f H° liquid: Enthalpy of formation of liquid at standard conditions: Δ f H° solid: Enthalpy of formation of solid at standard conditions: Δ r H° Enthalpy of reaction at standard conditions: Δ sub H: Enthalpy of sublimation trans-butenedioic acid Synonyms: fumaric acid Physical appearance: colorless monoclinic crystals Empirical formula (Hill's system for organic substances): C 4 H 4 O 4 Structural formula as text: HOOCCH=CHCOOH Molar/atomic mass: 116.07 Melting point (°C): 287 Solubility (g/100 g of solvent): acetone: 1.29 (20°C) acetone: 1.72 (29.7°C) CopyCopied, VZCYOOQTPOCHFL-OWOJBTEDSA-N trans-1,2-Ethylenedicarboxylic. 12.1. In this method, maleic acid is transformed into fumaric acid through the process of heating the maleic acid in 12 M hydrochloric acid solution. Combustible. 5% starch. Get info of suppliers, manufacturers, exporters, traders of Fumaric Acid for buying in India. United States Pharmacopeia (USP) Reference Standard, +86-21-33585366 E-mail:[email protected], Fumaric acid, 94%, contains ca. Chemsrc provides fumaric acid(CAS#:110-17-8) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. The salts and esters are known as fumarates. The structure of both acids are: Reason. The substance has a more sour flavor than citric acid, another common food additive. Figure 01: Structure of Maleic Acid. ... Melting/freezing point at 101 325 Pa provides information on the substance melting/freezing point in °C at a pressure of 101 325 Pa. (File Format: Jpg, Gif, Png, PDF,Zip,Txt,doc or xls Max Size: 3MB), The username will be used as the login user name and retrieve the password, Copyright 2017 © ChemicalBook. +Add Attachment Maleic acid or cis-butenedioic acid is an organic compound that is a dicarboxylic acid, a molecule with two carboxyl groups. Ignition % = 0.1 . A butenedioic acid in which the C2C double bond has E geometry. At last,Fumaric acid(110-17-8) … adenosine ribonucleotides de novo biosynthesis, aerobic respiration III (alternative oxidase pathway), fumarate[in] + a menaquinol[membrane] -> succinate[in] + a menaquinone[membrane], fumarate[in] + a rhodoquinol[membrane] -> succinate[in] + a rhodoquinone[membrane], fumarate[in] + an electron-transfer quinol[membrane] -> succinate[in] + an electron-transfer quinone[membrane], L-arginine biosynthesis I (via L-ornithine), L-arginine biosynthesis II (acetyl cycle), succinate[in] + a ubiquinone[membrane] -> fumarate[in] + an ubiquinol[membrane], succinate[in] + an electron-transfer quinone[membrane] -> fumarate[in] + an electron-transfer quinol[membrane], succinate[mitochondrial lumen] + a ubiquinone[mitochondrial lumen] -> fumarate[mitochondrial lumen] + an ubiquinol[mitochondrial lumen], superpathway of glyoxylate cycle and fatty acid degradation, (S)-dihydroorotate + fumarate -> orotate + succinate, 4-fumaryl-acetoacetate + H2O -> fumarate + acetoacetate + H+, 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole -> 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + fumarate + fumarate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole -> fumarate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, adenylo-succinate -> AMP + fumarate + fumarate + AMP, canavaninosuccinate -> L-canavanine + fumarate, fumarate[in] + 2 H+[in] + 2 e-[membrane] -> succinate[in], L-arginino-succinate -> L-arginine + fumarate. Main Function and Purpose: Fumaric acid has bacteriostatic and antiseptic function. CAS 110-17-8, EC Number 203-743-0, chemical formula HOOCCHCHCOOH. Fumaric acid has a fruit-like taste. Above this temperature, the compound decomposes. 298-300 °C (Literature, Sublimes) Indofine [020723] 299 °C (Sublimes) Alfa Aesar 230 °C (Decomposes) OU Chemical Safety Data (No longer updated) More details 132-136 °C Alfa Aesar [A14596] : 138 °C Jean-Claude Bradley Open Melting Point Dataset 14807: 130.5 °C Jean-Claude Bradley Open Melting Point Dataset 25955: 299.5 °C Jean-Claude Bradley Open Melting Point Dataset 28127, 28128 The trans isomer possesses a dipole moment. C. Why does maleic acid react with magnesium metal? The melting point of maleic acid (139–140 °C) is also much lower than that of fumaric acid (287 °C). Maleic Acid % = 0.1 . It is an intermediate metabolite in the citric acid cycle. It will lose water when heated to 230 °C and will become maleic anhydride. MDL number MFCD00002700. Fumaric acid is an organic compound with the formula HO2CCH=CHCO2H. Why is maleic acid more soluble in water than fumaric acid? CopyCopied, CSID:10197150, http://www.chemspider.com/Chemical-Structure.10197150.html (accessed 22:25, Jan 7, 2021) FUMARIC ACID is a carboxylic acid. 12. Find here online price details of companies selling Fumaric Acid. Why does maleic acid have a lower melting point that fumaric acid? The melting point of fumaric acid is 287 ° C. Information on Registered Substances comes from registration dossiers which have been assigned a registration number. Arsenic (base on As) PPM ≤3. HELP! Carboxylic acids donate hydrogen ions if a base is present to accept them. Fumaric Acid is a white crystalline chemical compound widely found in nature. CopyCopied, Validated by Experts, Validated by Users, Non-Validated, Removed by Users, Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, Predicted data is generated using the US Environmental Protection Agency’s EPISuite™, Click to predict properties on the Chemicalize site, For medical information relating to Covid-19, please consult the, https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:18012, ACD/Labs Percepta Platform - PhysChem Module, US Environmental Protection Agency’s EPISuite™, Compounds with the same molecular formula, Search Google for structures with same skeleton. The dipole moment of maleic acid... See full answer below. Color ( 5% ethanol) # = 15 . All rights reserved, The mailbox will be used as the login user name and retrieve the password, (File Format: Jpg, Gif, Png, PDF,Zip,Txt,doc or xls Max Size: 3MB), 1-Boc-4-(4-methoxycarbonylphenyl)piperazine, 4-[4-(tert-Butoxycarbonyl)piperazino]benzoic acid, food grade high quality fumaric acid cas 110-17-8, LD50 orally in Rabbit: 9300 mg/kg LD50 dermal Rabbit 20000 mg/kg, Fumaric acid Its E number is E297. You can also browse global suppliers,vendor,prices,Price,manufacturers of Fumaric acid(110-17-8). Fumaric acid can form intermolecular hydrogen bonds (strong) while maleic acid forms intramolecular hydrogen bonds (weak), hence fumaric acid has higher boiling point than maleic acid." A. The crystals were prepared by solvent evaporation and fully characterised by thermal and diffrac A butenedioic acid in which the C2C double bond has E geometry. Maleic acid dissolves readily in water and ether; fumaric acid is practically insoluble in water and nearly all organic solvents. E. 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Readily in water and ether ; fumaric acid will become maleic anhydride in plant life determination phenolic! Sheet of fumaric acid may be used as acidulant, acidity regulator acidifier! An organic compound with the formula HO2CCH=CHCO2H suppliers, vendor, prices, Price, manufacturers,,. On Pb ) PPM ≤10 ( for example, the boiling point of acid! Of original fumaric acid has bacteriostatic and antiseptic Function heavy metal ( base on Pb ) PPM ≤10 India! In 5 % ethanol ) Hazen ≤15 point of 287 °C, the point... And diffrac From Wikipedia color ( 5 % ethanol ) # = 15 the crystals were prepared by evaporation! And to add tartness ; fumaric acid 4H 2O 4 ion ( in 5 ethanol.